Extremely high risk of addiction, often after just a few uses
Severe damage to the heart, including heart attacks, arrhythmias, and high blood pressure
Stroke risk due to blood vessel constriction and reduced oxygen to the brain
Lung damage (from smoking), leading to chronic cough, shortness of breath, or respiratory failure
Neurological damage including seizures, memory loss, and long-term cognitive decline
Psychiatric complications such as paranoia, hallucinations, violent behavior, and depression
Severe weight loss and malnutrition due to appetite suppression
Social consequences such as financial instability, legal problems, and damaged relationships